Federal update: DOJ partially rescheduled medical cannabis to Schedule III (April 28, 2026 final order). State-licensed medical operators may apply for expedited DEA registration through June 27, 2026; DEA hearing on full rescheduling set for June 29, 2026.

What Initiative 437 Actually Does

Initiative 437 takes a practitioner-judgment approach rather than a fixed list of qualifying conditions. A patient (any age) qualifies if a "health care practitioner" (MD, DO, PA, NP licensed in Nebraska or licensed elsewhere and "practicing in compliance with the Uniform Credentialing Act") issues a "valid signed and dated declaration" that "the potential benefits of cannabis outweigh the potential harms" for the patient’s condition. Possession limit: up to 5 ounces. Caregivers permitted by signed affidavit. Home cultivation NOT permitted. No fixed qualifying-conditions list — deliberate choice to avoid bottlenecks.

Last verified: May 2026

Patient Eligibility — Practitioner-Judgment Standard

Initiative 437 takes a practitioner-judgment approach rather than a fixed list of qualifying conditions. A patient (any age, including minors and patients under guardianship) qualifies if a "health care practitioner" issues a "valid signed and dated declaration" that, "in the practitioner’s professional judgment, the potential benefits of cannabis outweigh the potential harms for the alleviation of a patient’s medical condition, its symptoms, or side effects of the condition’s treatment."

Definition of "Health Care Practitioner"

A "health care practitioner" includes:

  • Any licensed Nebraska MD (medical doctor).
  • Any licensed Nebraska DO (doctor of osteopathy).
  • Any licensed Nebraska PA (physician assistant).
  • Any licensed Nebraska NP (nurse practitioner).
  • Any practitioner licensed elsewhere who is "practicing in compliance with the Uniform Credentialing Act."

This was a deliberate choice to avoid fixed "qualifying conditions" lists that have become bottlenecks in other states. Many states (Florida, Texas, Pennsylvania, Mississippi) restrict medical cannabis to a fixed list of conditions; Nebraska’s practitioner-judgment standard is more flexible.

Conditions Advocates Cited

Although I-437 does not statutorily require any specific qualifying conditions, the conditions advocates publicly cited as motivating the measure include:

  • Cancer and cancer-treatment side effects.
  • Glaucoma.
  • AIDS / HIV.
  • Amyotrophic lateral sclerosis (ALS).
  • Alzheimer’s disease.
  • Hepatitis C.
  • Multiple sclerosis (MS) including spasticity.
  • Crohn’s disease.
  • Epilepsy (including pediatric severe epilepsy — the Eggers / Gillen / Bronson family stories).
  • Post-traumatic stress disorder (PTSD).
  • Chronic pain.
  • Chronic and intractable nausea.
  • Tourette’s syndrome.
  • Autism spectrum disorders.
  • Severe arthritis.
  • Terminal illness.
  • Severe spinal-cord injury.

None of these is statutorily required for patient eligibility. Practitioner discretion governs.

Possession Limit — 5 Ounces

Patients and caregivers may possess an "allowable amount" — defined as up to 5 ounces of cannabis at any given time. The 5 ounces does not include the weight of any other ingredient combined with cannabis in topicals, foods, drinks, tinctures, or other preparations — meaning the 5-ounce cap is on cannabis content, not full product weight.

Caregivers

Adult patients (18+) may designate a caregiver in a signed affidavit; caregivers must be at least 21. For minor patients or patients under guardianship, the caregiver is the parent / legal guardian or a person designated by sworn affidavit.

Home Cultivation NOT Permitted

Initiative 437 does not authorize home growing. Cultivation remains a Class IIA felony under § 28-416. The 4 commission-approved cultivators are the only legal cannabis cultivators in Nebraska. See cultivators page.

30-Day / 90-Day Supply Caps (Commission Imposed)

The April 2026 formal regulations from the Nebraska Medical Cannabis Commission clarify that purchase is limited to up to 5 ounces per 30 days per patient and no more than 5 grams of delta-9 THC per patient from the same dispensary in any 90-day period. These restrictions are imposed by the commission, not by the initiative itself. Advocates challenge them as inconsistent with voter intent and may litigate.

DHHS Patient Registry — Status

Initiative 437 originally contemplated DHHS maintaining a voluntary patient registry. As of May 2026, no statewide patient registry has been launched. DHHS opposed the ballot measures and remains lukewarm on implementation; Roger Donovick, DHHS executive medical officer, testified against multiple legislative bills citing federal Schedule I status. The April 13, 2026 regulations require dispensary access only for patients with a recommendation from an in-state physician registered with the program — narrower than what voters approved. As of May 2026, advocates and lawmakers say no Nebraska physician has publicly registered to issue medical-cannabis recommendations, citing fear of license discipline by DHHS and possible retaliation by AG Hilgers.

What I-437 Does NOT Provide

  • No employment protection — Nebraska is at-will employment. Sponsors deliberately stripped employment provisions to satisfy single-subject rule.
  • No housing protection.
  • No child-custody protection.
  • No professional-licensing protection.
  • No DUI defense.
  • No federal-employment protection — Schedule I federal status persists pending DOJ rulemaking.
  • No security-clearance protection.
  • No home-cultivation right.

Practical Patient Notes

  • Document your recommendation — keep your signed practitioner declaration, dosage instructions, and product labeling on you. The affirmative defense requires the recommendation be in your possession.
  • Out-of-state telehealth recommendations are reportedly being used by some Nebraska patients.
  • Watch the litigation — Kuehn v. Evnen NE Supreme Court ruling pending could affect patient-protection portion.
  • Federal employment / security clearance — even with valid recommendation, federal-employee or federally-cleared individuals face categorical exposure.

Related on this site: Nebraska 5 oz / 30-Day Supply Rule, Nebraska Medical Cannabis Commission, Nebraska Initiatives 437 & 438 (2....